DESIGN AND SYNTHESIS OF LACTAMS DERIVED FROM MUCOCHLORIC AND MUCOBROMIC ACIDS AS PSEUDOMONAS AERUGINOSA QUORUM SENSING INHIBITORS

Design and Synthesis of Lactams Derived from Mucochloric and Mucobromic Acids as Pseudomonas aeruginosa Quorum Sensing Inhibitors

Bacterial infections, particularly hospital-acquired infections caused by Pseudomonas aeruginosa, have become a global threat with a high mortality rate.Gram-negative bacteria including P.aeruginosa employ N-acyl homoserine lactones (AHLs) as chemical signals to regulate the expression of pathogenic phenotypes through a mechanism called quorum panc

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MmpL Proteins in Physiology and Pathogenesis of M. tuberculosis

Mycobacterium tuberculosis (Mtb) remains an important human pathogen.The Mtb cell envelope is a critical bacterial structure that contributes to virulence and pathogenicity.Mycobacterial membrane protein large (MmpL) proteins export bulky, hydrophobic substrates that are essential for accel lifetime horse supplement the unique structure of the cell

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Quantifying the invasiveness of species

The success of invasive species has been explained by two contrasting but non-exclusive views: (i) intrinsic factors make some species inherently good invaders; (ii) species become invasive as a result of extrinsic ecological and genetic influences cirque colors lavender sky such as release from natural enemies, hybridization or other novel ecologi

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